{"id":1989,"date":"2012-09-20T18:36:20","date_gmt":"2012-09-20T16:36:20","guid":{"rendered":"http:\/\/130.238.147.106\/jakobssonlab\/?p=1989"},"modified":"2025-02-18T15:43:05","modified_gmt":"2025-02-18T14:43:05","slug":"paper-on-adaptation-and-complex-african-history-published-in-science","status":"publish","type":"post","link":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/2012\/09\/20\/paper-on-adaptation-and-complex-african-history-published-in-science\/","title":{"rendered":"Paper on adaptation and complex African history published in Science"},"content":{"rendered":"\n

Carina Schlebusch is the first author of the paper \u201cGenomic variation in seven Khoe-San groups reveals adaptation and complex African history<\/a>\u201d, published in Science. The\u00a0paper\u00a0received ample attention by scientific and popular media, e.g.: CBS News,\u00a0Science News,\u00a0\u00a0Nature<\/a>,\u00a0Science daily<\/a>,\u00a0Spiegel<\/a>,\u00a0AAAS<\/a>,\u00a0Swedish public television (SVT)<\/a>, Kwela (Afrikaans \u2013 television), Swedish radio (SR1<\/a>,\u00a0SR2<\/a>),\u00a0UNT<\/a>,\u00a0DN<\/a>, Business Day, Diamond Fields Advertiser, Die Burger, Die Son, Die Volksblad, Kalahari Bulletin, Mercury, Pretoria News, Rapport, The Star, Morning Live (TV show), SABC News (TV), RSG Radio station.<\/p>\n\n\n\n

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Cave painting in South Africa: The modern hunter-gatherer culture of the San is said to have existed 44,000 years ago. Photograph: Carina Schlebusch.<\/figcaption><\/figure>\n\n\n\n

Abstract<\/h2>\n\n\n\n

The history of click-speaking Khoe-San, and African populations in general, remains poorly understood. We genotyped \u223c2.3 million single-nucleotide polymorphisms in 220 southern Africans and found that the Khoe-San diverged from other populations \u2265100,000 years ago, but population structure within the Khoe-San dated back to about 35,000 years ago. Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa; instead, it indicated a history of admixture and stratification. We found evidence of adaptation targeting muscle function and immune response; potential adaptive introgression of protection from ultraviolet light; and selection predating modern human diversification, involving skeletal and neurological development. These new findings illustrate the importance of African genomic diversity in understanding human evolutionary history.<\/p>\n\n\n\n

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Related content<\/h2>\n\n\n\n
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New DNA study shows humankind\u2019s complex origins in Africa<\/h2>\n\n\n\n
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UU Press Release<\/a><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Carina Schlebusch is the first author of the paper \u201cGenomic variation in seven Khoe-San groups reveals adaptation and complex African […]<\/p>\n","protected":false},"author":1,"featured_media":1990,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,24,12,18,11,1],"tags":[134,14,98,36,55],"class_list":["post-1989","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-highlights","category-in-the-media","category-news","category-publications","category-research","category-uncategorized","tag-adaptation","tag-africa","tag-archaeogenomics","tag-human-past","tag-population-genetics"],"_links":{"self":[{"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/posts\/1989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/comments?post=1989"}],"version-history":[{"count":2,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/posts\/1989\/revisions"}],"predecessor-version":[{"id":2798,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/posts\/1989\/revisions\/2798"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/media\/1990"}],"wp:attachment":[{"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/media?parent=1989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/categories?post=1989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jakobssonlab.iob.uu.se\/index.php\/wp-json\/wp\/v2\/tags?post=1989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}