Lactase Persistence Alleles Reveal Partial East African Ancestry of Southern African Khoe Pastoralists

Gwenna Breton

In a new study Breton et al. (2014) show how lactase persistence variants tell the story about the ancestry of the Khoe people in southern Africa.

Highlights

  • •East African LP variant occurs at high frequency in southern African pastoralist Khoe
  • •A small but distinct (13%) fraction East African ancestry in the Nama (a Khoe group)
  • •We find genetic evidence of adaptation for consuming lactose in Khoe-speaking groups
  • •Pastoralist practices were brought to southern Africa by migration from East Africa

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Lactase persistence alleles reveal ancestry of southern African Khoe pastoralists