Category: Research
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Tales of Human Migration, Admixture, and Selection in Africa
A review article by Carina and Mattias was published in the Annual Reviews, Annual Review of Genomics and Human Genetics, vol. 19, 2018. Abstract In the last three decades, genetic studies have played an increasingly important role in exploring human history. They have helped to conclusively establish that anatomically modern humans first appeared in Africa…
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Investigating Holocene human population history in North Asia using ancient mitogenomes
Members of the group were involved in a study published in the Scientific Reports. Analyses of complete mitochondrial genomes of 41 ancient humans from North Asia revealed long-term genetic continuity in the region. We further detected signatures of gene flow or population structure, altogether highlighting the complexity of human demographic history. Abstract Archaeogenomic studies have largely…
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Four millennia of Iberian biomolecular prehistory illustrate the impact of prehistoric migrations at the far end of Eurasia
The team was involved in a multidisciplinary study highlighting the temporal genetic changes caused by prehistoric migrations into Iberia. The analyses of ancient human remains shed light into the origin of farming life-style in the far west of Eurasia. The study is published in PNAS. Significance The gene pool of modern Europeans was shaped through prehistoric…
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New insights on cultural dualism and population structure in the Middle Neolithic Funnel Beaker culture on the island of Gotland
Magdalena Fraser and others have published new insights into the Neolithic Funnel-Beaker culture. This multidisciplinary article in the Journal of Archaeological Science: Reports and revealed intriguing results regarding the genetics, diet, and culture of this ancient human population. Highlights Abstract In recent years it has been shown that the Neolithization of Europe was partly driven by…
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Ancient human DNA: How sequencing the genome of a boy from Ballito Bay changed human history
Carina and Mattias were involved in a commentary article in the South African Journal of Science describing the scientific merits of the genome of a ancient boy from South Africa.
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Patterns of variation in cis-regulatory regions: examining evidence of purifying selection
Thijessen and others from the group highlighted the genomic signatures of purifying selection under consideration of confounding factors such as demography. The results appeared in BMC Genomics. Abstract Background With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much…