Tag: methods
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Tweap protocol—Lets Tweap again: Economic and SNP retrieval optimisation for target enrichment of ancient DNA
The protocol (closely related to the preprint described below) has been updated and published in April 2026 (Open Access): Saupe, T., Tan, E. J., Gómez, M. O., Bernhardsson, C., & Jakobsson, M. (2026). Tweap protocol for target enrichment via in-solution hybridisation using Twist Bioscience Panels. protocols.io. DOI: https://www.protocols.io/view/tweap-protocol-for-target-enrichment-via-in-soluti-5qpvoknbxl4o/v1 An updated preprint from the Jakobsson Lab:…
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Analysis of the abundance of radiocarbon samples as count data
de Navascués, M., Burgarella, C., & Jakobsson, M. (2025). Analysis of the abundance of radiocarbon samples as count data. Peer Community Journal, 5. https://doi.org/10.24072/pcjournal.522 Abstract The analysis of the abundance of radiocarbon samples through time has become a popular method to address questions of demography in archaeology. The history of this approach is marked by the use…
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Patterns of variation in cis-regulatory regions: examining evidence of purifying selection
Thijessen and others from the group highlighted the genomic signatures of purifying selection under consideration of confounding factors such as demography. The results appeared in BMC Genomics. Abstract Background With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much…